1. Introduction The insulin-producing β-cells of the pancreatic islets play a central role in the regulation of blood glucose. Dysfunction or loss of these cells is a key step in the development of both type 1 and type 2 diabetes. Understanding β-cell […]
Introduction Beta-cell destruction is a central pathogenic event in the development of diabetes mellitus, particularly in type 1 diabetes (T1D) and, to a lesser degree, in advanced type 2 diabetes (T2D). Pancreatic beta cells, located in the islets of Langerhans, are responsible […]