Introduction Antiplatelet therapy is a cornerstone of modern cardiovascular and cerebrovascular medicine. Platelets play a crucial role in hemostasis by forming clots to stop bleeding. However, abnormal platelet activation and aggregation can lead to thrombosis, which is the underlying cause of many […]
Introduction Platelets are small, anucleate blood cells that play a fundamental role in hemostasis and thrombosis. Their ability to adhere, activate, and aggregate is crucial for the formation of a hemostatic plug at sites of vascular injury. However, excessive or inappropriate platelet […]
Introduction Platelet aggregation is a fundamental physiological process that plays a vital role in hemostasis, wound healing, and thrombosis. When vascular injury occurs, platelets rapidly adhere to the damaged endothelium, become activated, and clump together to form a platelet plug. This process […]
Introduction Clopidogrel is an oral antiplatelet drug from the thienopyridine class. It is widely prescribed to prevent thrombotic cardiovascular events in patients with atherosclerosis, myocardial infarction (MI), ischemic stroke, or peripheral artery disease (PAD). Since its approval in the 1990s, it has […]